Scotland co-captain Rory Darge returns from injury to start in the back-row. Jack Dempsey also comes into the starting XV at number eight. The injured Luke Crosbie and Jamie Ritchie drop out. In the second row the injured Richie Gray is replaced by Grant Gilchrist.
Scotland have been forced into some late adjustments. Kyle Steyn has had to drop out as his wife has gone into labour. So Kyle Rowe switches to the wing and Harry Paterson comes in to make his debut at full-back.
Scotland: Paterson; Rowe, H Jones, Tuipulotu, Van der Merwe; Russell (co-capt), White; Schoeman, Turner, Z Fagerson, Gilchrist, Cummings, M Fagerson, Darge (co-capt), Dempsey.
Replacements: Ashman, Hepburn, Millar-Mills, Skinner, Christie, G Horne, Healy, Redpath.